NNMT Inhibitor | Fat Reduction, NAD+ Enhancement & Longevity Research | For Research Use Only

5-Amino-1MQ (1-Methylquinolinium-5-Amidrazone) is a small molecule NNMT (Nicotinamide N-Methyltransferase) inhibitor studied for its ability to increase intracellular NAD+ levels, activate SIRT1, and enhance metabolic performance. This compound is of growing interest in fields such as obesity, type 2 diabetes, anti-aging, and cellular energy optimization.

By blocking NNMT, 5-Amino-1MQ allows for greater availability of NAD+ precursors, which improves mitochondrial function, insulin sensitivity, and promotes fat loss in preclinical research.

🔍 Key Features

• Inhibits NNMT – Helps preserve NAD+ and modulate energy metabolism

• Fat Cell Shrinkage – Demonstrated reduction of adipocyte size in animal studies

• Supports Longevity Pathways – Promotes SIRT1 and mitochondrial efficiency

• Improves Insulin Response – Research shows potential in glucose tolerance enhancement

• Cellular Optimization – Ideal for metabolic, anti-obesity, and age-related decline models

⚙️ Compound Details

• Chemical Name: 1-Methylquinolinium-5-Amidrazone

• Common Name: 5-Amino-1MQ

• CAS Number: 14092-12-5

• Molecular Formula: C₁₀H₁₂N₄

• Molecular Weight: ~188.23 g/mol

• Purity: ≥ 98% (HPLC Verified)

• Form: Lyophilised white/off-white powder

• Unit Size: 50mg per vial

🧊 Storage & Handling

• Storage (lyophilised): Store at –20°C, away from light and moisture

• Reconstitution: Use sterile bacteriostatic water or DMSO (for in vitro use)

• Post-Reconstitution: Store at 2–8°C and use within 5–7 days

• Avoid: Repeated freeze-thaw cycles

⚠️ For Research Use Only

5-Amino-1MQ – 50mg is provided strictly for scientific research purposes only. It is not for human use, therapeutic applications, or veterinary use. Must be handled by qualified professionals in secure laboratory environments.